DBCO-NHS ester

CAS No. 1353016-71-3

DBCO-NHS ester( DBCO NHS ester )

Catalog No. M11436 CAS No. 1353016-71-3

An amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 28 Get Quote
10MG 46 Get Quote
25MG 77 Get Quote
50MG 114 Get Quote
100MG 200 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    DBCO-NHS ester
  • Note
    Research use only, not for human use.
  • Brief Description
    An amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.
  • Description
    An amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine; A click chemistry tool used to conjugate DBCO-PEG4-MMAF to the introduced non-natural amino acid pAMF using a noncleavable linker.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    DBCO NHS ester
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADCs Linker/Click Chemistry
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1353016-71-3
  • Formula Weight
    430.45
  • Molecular Formula
    C25H22N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (124.25 mM)
  • SMILES
    O=C(CCC(ON1C(CCC1=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
  • Chemical Name
    Dibenz[b,f]azocine-5(6H)-butanoic acid,11,12-didehydro-γ-oxo-,2,5-dioxo-1-pyrrolidinyl es

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Currier NV, et al. Mol Cancer Ther. 2016 Jun;15(6):1291-300.
molnova catalog
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